Photodynamic Therapy (PDT)

Photodynamic Therapy (PDT) with Red Light

An advanced and effective treatment for precancerous lesions and superficial, early-stage cancerous lesions

Photodynamic therapy (PDT) is an advanced, non-invasive medical treatment based on applying an active substance to the skin followed by exposure to red light of a specific wavelength. The combination of the substance and the light causes targeted destruction of damaged cells, while preserving the surrounding healthy tissue as much as possible.

At On.Top we offer PDT with close medical support and excellent aesthetic results.

Similar to applying 5-FU cream (Efudex cream), photodynamic therapy makes it possible to treat a relatively large area of skin non-invasively, and even to heal precancerous and early cancerous lesions without a scalpel and usually without scars or marks. Unlike 5-FU cream, photodynamic therapy involves a short recovery period (down time) of only a few days, so it is also suitable for patients with a busy lifestyle who cannot afford to walk around with red skin for two to three months after treatment.

The effectiveness of photodynamic therapy varies depending on the lesion, and is generally slightly lower than that of treatment with 5-FU cream, but it is a good compromise between treatment effectiveness, side effects and the ability to stay with the treatment.

Photodynamic therapy is recognized by some insurance companies as a “surgery-alternative treatment”, so partial reimbursement of the cost can be obtained, depending on the policy.

Our team of experts will be happy to see you, assess the condition of your skin and tailor the most accurate treatment for you.

In conclusion

Photodynamic therapy (PDT) is a non-invasive procedure that combines applying an active substance and exposure to red light, for targeted destruction of damaged cells while preserving healthy tissue.

Recognized by most insurance companies
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Frequently asked questions

Questions and answers about the service

At our center you will find a team of experts: an experienced medical team focused on the diagnosis and treatment of melanoma and skin cancer, alongside a service team that handles all the administrative side
How is photodynamic therapy performed?

The treatment includes three stages:

  1. Preparing the area: Cleaning the skin and removing crusts/gentle scaling as needed, to allow optimal absorption of the active substance.
  2. Applying a photosensitizing substance: A substance (5-ALA 20% ointment) that is taken up by the problematic cells is applied to the skin.
    The incubation time varies, usually about three hours, depending on the type and location of the lesion.
  3. Exposure to red light: The treated area is exposed to a red light lamp at a specific frequency.
    At this stage the active substance becomes toxic to the inflamed or damaged cells and causes their selective destruction.

The treatment usually takes 60-90 minutes.

During the exposure to light, some patients report a sensation of warmth, burning or tingling.

If needed, the area can be cooled during treatment to significantly ease the sensation.

After treatment there may be redness, swelling or gentle peeling, which are transient effects indicating a normal therapeutic response.

  • Relatively high effectiveness for precancerous lesions.
  • Good aesthetic results, without incisions and without scars.
  • Effective treatment of large areas.
  • Short recovery time.
  • Repeat treatment as needed with no special limit.
  • Especially suitable for delicate areas such as the face, scalp, décolletage and the backs of the hands.

For 48-72 hours after treatment, avoid sun exposure, even indirect, and be sure to use high-protection sunscreen. Redness and peeling may last for several days.

In most cases one or two sessions are needed, depending on the physician’s assessment.

  • Treatment performed by experts in dermatology and skin tumors.
  • Treatment tailored personally by lesion type, skin type and medical history.
  • A holistic approach combining a full skin diagnosis with management of skin cancer risks.
  • A full support framework including diagnosis, treatment and ongoing follow-up.

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